Lacrisun Tonic 5%

• Leaflet

Product description

PATENTED PRODUCT The human cornea is the organ that allows the passage of light and its access to the posterior chamber of the eye. To working at its best, it must be in physiologically constant conditions of hydration. The modification of this state leads to the sufference of the organ and to a potential alteration of the vision. There are physio-pathological conditions that lead the cornea to have a state of excess hydration which ended in edema. This can happen due to post-surgical suffering, trauma and other specific conditions of the patient. Age is also an important risk factor; after the age of 50 the incidence is much more frequent. Lacrisun Tonic 5% is a preservative-free hypertonic ophthalmic solution, with the following composition: Sodium chloride 5%, Hyaluronic acid 0.2%, Amino acids (L-proline, L-leucine, L-glycine and L-lysine), Vitamin E TPGS, Riboflavin (Vitamin B2). It is a multidose bottle and, while opened, the product is stable for 180 days. The hyperosmolarity of the solution, essential for the healing of the corneal edema, is obtained through the high concentration of sodium chloride (5%). This therapeutic approach is now widely considered the one of choice for this kind of pathology. Hyaluronic acid of appropriate molecular weight performs the moisturizing and lubricating function necessary to counteract the symptoms of dry eye that could occur in these patients for a more or less short period. The administration of amino acids is important for the production of collagen and elastin, during the proliferation phase of tissue repair which is essential for creating new tissue. Furthermore, the amino acids are converted into precursors of lysyl oxidase and therefore can increase the speed of the natural healing process of the ocular surface. The amino acids therefore have the function of nourishing the corneal tissues and assisting the repair processes of corneal lesions. In Lacrisun, vitamin E-TPGS exerts the function of carrier for riboflavin (vitamin B2), in order to allow the passage of this substance across the corneal surface, positioning itself in the innermost layers of the cornea. In Lacrisun the administration of right quantities of riboflavin sufficient to be activated by the UVA of the solar spectrum (but much lower than those administered for the treatment of keratoconus) allow to activate, in addition to the primary process of crosslink guided by lysyl oxidase, also the crosslink mediated from riboflavin, thus doubling the chances of rapid tissue repair.

Composition

Sodium chloride 5% (w/v), sodium hyaluronate, sodium phosphate monobasic monohydrate, sodium phosphate dibasic dodecahydrate, L-proline, L-glycine, L-lysine hydrochloride, L-leucine, Riboflavin sodium phosphate (0.075%), Vitamin E TPGS, water for injectable preparation. Preservative free

Preservation

Close the bottle after the use: the content can be used up to 180 days after first opening. Store at a temperature below 30°C.